This finding has important implications for selecting crystalloid in pediatric living-donor liver transplantation. Conclusionsįor intraoperative fluid management in pediatric living-donor liver transplantation patients, lactated Ringer's solution administration was associated with a higher 90-day mortality rate than normal saline. Hospital-free days did not differ between groups (9 days vs.
The differences in particles mean that lactated Ringer’s doesn’t last as long in the body as. In the lactated Ringer's solution group, four (6.6%) recipients developed acute renal injury within 7 days postoperatively compared with three (4.9%) recipients in the normal saline group. Fluid manufacturers put slightly different components in normal saline compared to lactated Ringer’s. Early allograft dysfunction and primary nonfunction incidences were also more frequent in the lactated Ringer's solution group (19.7% and 11.5%, respectively) than in the normal saline group (3.3% and 0.0%, respectively). After matching, the lactated Ringer's solution group had a higher 90-day mortality rate than the normal saline group (11.5% vs. Propensity score matching identified 61 patients in each group. We included 333 pediatric patients who met the entry criteria for analysis. The primary outcome was 90-day all-cause mortality, and the secondary outcomes included early allograft dysfunction, primary nonfunction, acute renal injury, and hospital-free days (days alive postdischarge within 30 days of liver transplantation). The groups with comparable clinical characteristics were balanced by propensity score matching.
This single-center, retrospective trial study enrolled children who received either lactated Ringer's solution or normal saline during living-donor liver transplantation between January 2010 and August 2016.
To compare the effect between lactated Ringer's solution and normal saline for intraoperative volume replacement on clinical outcomes among pediatric living-donor liver transplantation patients. In pediatric living-donor liver transplantation, lactated Ringer's solution and normal saline are commonly used for intraoperative fluid management, but the comparative clinical outcomes remain uncertain.